surfaces of the oxygenator and cardiotomy/venous reservoir are coated with either: Carmeda®* BioActive Surface. • Durable, non-leaching End Point. Attached

end-point attachment mechanism (CARMEDA® BioActive Surface (CBAS® Surface)) which serves to anchor heparin molecules to the luminal surface while still maintaining heparin’s intrinsic bioactive properties. The result is a proven thromoresistant surface with a long-term, safe clinical history.

Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX vascular graft performance by Carmeda BioActive surface heparin immobilization. Eur J Vasc Endovasc Surg. 2003;25:432–437 Evaluation of Carmeda bioactive surface (CBAS), Duraflo II and a novel nonspecific protease-modified surface using a new in vitro model simulating cardiopulmonary bypass. Yii M(1), Gourlay T, Fleming J, Matata B, Taylor KM. Author information: (1)Department of Cardiothoracic Surgery, Hammersmith Hospital, London. Almost 700 global scientific reports have been published on the chemistry, biological properties, safety and clinical performance of the CARMEDA ® BioActive Surface technology. Follow the link below for an extensive list of publications on CARMEDA ® BioActive Surface (also known as CBAS ® Heparin Surface).

This technology provides a lasting thromboresistance that actively prevents platelet adhesion and thrombus formation on medical device surfaces. What is the abbreviation for Carmeda BioActive Surface? What does CBAS stand for? CBAS abbreviation stands for Carmeda BioActive Surface. 2014-10-31 · Medtronic initiated an Urgent Medical Device Recall for 66 distributed Affinity FusionTM Oxygenation Systems with Carmeda Bioactive Surface due to damaged heat exchangers. Product affected by this issue is limited to model CB841 sold stand alone or incorporated in Total Systems TS1614R1 and TS1595R7. Carmeda has a staff of dedicated people in a range of fields, such as Research & Development, Quality Assurance, and Manufacturing.

The left atrium was cannulated using a Carmeda bioactive surface cannula. Distal cannulation sites were the left common femoral artery or the aorta below the involved segment. The cannulae were connected to a BioMedicus centrifugal pump via Carmeda bioactive surface tubings and pump heads. No systemic heparin was used.

Affinity CP Centrifugal Blood Pump Brochure. 4 Pages.

2003-05-01 · One of the most clinically successful heparin technologies has been the Carmeda ® BioActive Surface (CBAS).12, 13 This heparin binding technology is based upon covalent end-point attachment of heparin to a biomaterial surface, enabling maintenance of functional heparin bioactivity.

Improvements in GoreTex vascular graft performance by Carmeda bioactive surface heparin immobilization. Eur J Vasc Endovasc Surg.

Metoden har kommersialiserats i Sverige och USA som Carmeda Bioactive Surface Our Carmeda BioActive Surface (CBAS®) is the most clinically proven of all hemocompatible coating technologies. World leader in hemocompatible coatings for Do plant produced bioactive compound affect occurrence of enteric bacteria in hygiene in surface water and hygiene standards for irrigation water as well as pediatric surgery owing to the relatively larger blood-artificial surface interface fully heparinized circuit (Carmeda Bioactive Surface, CBAS [Medtronic Inc]). Ytan som är i kontakt med blod är täckt med Carmeda Bioactive Surface (CBAS TM )för att minska trombrisken. Eftersom pumpen är transparent CARMEDA ® BioActive Surface är en av de mest välkända och kliniskt erkända homeokompatibla beläggningsteknologier som finns idag på den globala Carmeda AB,556639-2329 - På allabolag.se hittar du , bokslut, nyckeltal, koncern, koncernträd, styrelse, Status, varumärken, adress mm för Carmeda AB. Expanded knowledge on silk assembly for development of bioactive silk coating can be used to make surface coatings on biomedical materials. When functionalizing the silk with bioactive motifs and domains, the coatings with Sr, Mg and Si for spinal fusion: Surface characterization and biological evaluation. on single crystalline rutile: a model system for bioactive surfaces. Surface Reactions of Mesoporous Bioactive Glasses Monitored by Solid-State NMR: Concentration Effects in Simulated Body Fluid, C. Turdean-Ionescu, Carmeda AB – Org.nummer: 556639-2329.
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Immobilization of the water-soluble synthetic polymer, polyethylene glycol (PEG, –CH 2 CH 2 O–), is a widely used approach to making a biomaterial surface more protein and cell resistant. It also makes the surface hydrogel-like. Ultra-smooth, flow-optimized blood contact surfaces with CARMEDA ® BioActive Surface* coating for the best possible blood compatibility Safe de-airing through de-airing port Blood pumps with tri-leaflet valves made of polyurethane and blood pumps with bileaflet valves made of carbon The BioActive luminal surface of a 3 mm diameter GORE ® PROPATEN ® Vascular Graft (top) remains free of thrombus, while the non-bioactive surface of a control graft (below; 3 mm diameter) is covered with thrombus.

Freeman J, Chen A, Weinberg RJ, Okada T, Chen C, Lin PH. Begovac PC, Thomson RC, Fisher JL, et al. Improvements in GoreTex vascular graft performance by Carmeda bioactive surface heparin immobilization. Eur J Vasc Endovasc Surg.
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Clinical Durability of the CARMEDA BioActive Surface in EXCOR Ventricular Assist Device Pumps. Werkkala K, Jokinen JJ, Soininen L, Dellgren G, Hallhagen S

It also makes the surface hydrogel-like. Ultra-smooth, flow-optimized blood contact surfaces with CARMEDA ® BioActive Surface* coating for the best possible blood compatibility Safe de-airing through de-airing port Blood pumps with tri-leaflet valves made of polyurethane and blood pumps with bileaflet valves made of carbon The BioActive luminal surface of a 3 mm diameter GORE ® PROPATEN ® Vascular Graft (top) remains free of thrombus, while the non-bioactive surface of a control graft (below; 3 mm diameter) is covered with thrombus. Grafts were explanted after 2 hours in a challenging carotid shunt canine model.

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Material and Methods: this study investigated the utility of heparin immobilization onto expanded polytetrafluoroethylene using Carmeda® BioActive Surface technology (CBAS-ePTFE) as a means of improving vascular graft thromboresistance. Graft luminal surfaces were covered uniformly with the stably bound, end-point immobilized heparin.

† Also referred to as the GORE ® VIABAHN Endoprosthesis with PROPATEN Bioactive Surface in some regions. ‡ The heparin technology of the CARMEDA® BioActive Surface is marketed as the CBAS Heparin Surface for Gore vascular devices. Material and Methods: this study investigated the utility of heparin immobilization onto expanded polytetrafluoroethylene using Carmeda® BioActive Surface technology (CBAS-ePTFE) as a means of improving vascular graft thromboresistance. Graft luminal surfaces were covered uniformly with the stably bound, end-point immobilized heparin. What is the abbreviation for Carmeda BioActive Surface? What does CBAS stand for? CBAS abbreviation stands for Carmeda BioActive Surface.

End-point covalent linkage of heparin to polymer surfaces was first made commercially available as Carmeda Bioactive SurfaceTM (Carmeda, Switzerland ),

Carmeda AB har 40 anställda och gjorde ett resultat på 127 125 KSEK med omsättning 215 982 KSEK under 2001 jämförde de kliniska resultaten från 1336 patienter med Carmeda Bioactive Surface och Duraflo II-beläggningarna. Forskarna drog The CARMEDA ® BioActive Surface is a heparin-based coating designed to actively reduce thrombus formation on blood contacting medical devices.

The CBAS Heparin Surface stays on the surface and remains bioactive on the EXCOR pump at least up until 1 year. This is an important demonstration of coating durability and supports the mid-term and long-term clinical use as bridge-to-heart transplantation or to myocardial recovery. In the following experiments, we evaluated the heparin-bonded Carmeda Bioactive Surface (Medtronics Cardiopulmonary, Anaheim, Calif.) in an in vitro model of extracorporeal circulation at standard-dose heparin (5 U/ml), to examine the effects of the surface treatment on activation of blood elements, and at reduced-dose heparin (1 U/ml), to determine whether surface-bound heparin would serve as an effective anticoagulant. The CBAS Heparin Surface stays on the surface and remains bioactive on the EXCOR pump at least up until 1 year.