In four of these Ljungan virus was found in the stillborn children as well. A control group of twenty women with normal pregnancies showed that each of their placentas was free from the virus. In a corresponding follow up study the scientists found Ljungan virus in the placenta and/or children of all of the five cases examined.
No Ljungan Virus RNA in Stool Samples. From the Norwegian Environmental. Triggers of Type 1 Diabetes (MIDIA). Cohort Study. GERMAN TAPIA, MSC. 1,2.
The river runs through the Swedish counties of Jämtland and Västernorrland. The Ljungan Virus - A Novel Pathogen The Ljungan virus was discovered in the mid-1990s. The initial findings were made among bank voles, which are the most common mammal in Scandinavia. The Ljungan virus was later discovered in several animal species causing diseases such as diabetes, perinatal death and malformations in several animal species.
Men svenska virusjägare är detta virus på spåren, och via media har vi fått rapporter om deras framsteg. Nu senast i SVT. Ljungan virus (LV), has been isolated from these animals. If CD-1 mice, that normally do not carry LV, are infected with this virus in utero and exposed to stress after birth, the male offspring get type 2 diabetes. In BB rats LV was found in both prediabetic- and diabetic DPBB … Relationship Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children Anna-Lena Nilsson,1,2 Fariba Vaziri-Sani,2 Cecilia Andersson,2 Karin Larsson,3 Anneli Carlsson,2 Elisabeth Cedervall,4 Bjo¨rn Jo¨nsson,5 Jan Neiderud,6 Helena Elding Larsson,2 Sten-Anders Ivarsson,2 and A˚ke Lernmark2 Abstract Ljungan virus (LV), which belongs to the Parechovirus genus in the Picornaviridae family, was first isolated from bank voles (Myodes glareolus) in Sweden in 1998 and proposed as a zoonotic agent.To improve knowledge of the host association and geographical distribution of LV, tissues from 1685 animals belonging to multiple rodent and insectivore species from 12 European countries were … Molecular characterization of a novel Ljungan virus (Parechovirus; Picornaviridae) reveals a fourth genotype and indicates ancestral recombination. J Gen Virol.
Ljungan virus antibody RBA Coupled in vitro transcription translation of the Ljungan virus isolate 87-012 representing 812 amino acids (6-817) of the LV-1 protein [Johansson et al., 2002] in a pCRII-TOPO vector [Nilsson et al., 2009; Nilsson et al., 2013] was performed in a reaction mixture containing 2
2013). Ljungan virus (LV) is a picornavirus originally isolated from Swedish bank voles ( Myodes glareolus ) in 1998. The association of LV with human disease has been debated ever since, but fundamental The virus is a suspected human pathogen. Evidence: Literature Reference: PMID: 12163611: Authors: Johansson S, Niklasson B, Maizel J, Gorbalenya AE, Lindberg AM Title: Molecular analysis of three Ljungan virus isolates reveals a new, close-to-root lineage of the Picornaviridae with a cluster of two unrelated 2A proteins.
Bank voles (Clethrionomys glareolus) kept in captivity develop diabetes mellitus to a significant extent. Also in wild bank voles, elevated blood glucose has been observed. A newly isolated picornavirus named Ljungan virus (LV) has been found in the pancreas of these bank voles. Moreover, LV infecti …
Scientific publication av B Andersson — Nyligen har ett nytt virus isolerats från sork infångad vid floden Ljungan i Medelpad varför virus benämns Ljunganvirus. Detta virus tillhör liksom enterovirus Sammanfattning: Ljungan virus (LV) is a recently identified picornavirus of the genus Parechovirus. LV has been isolated from voles trapped in Sweden and also [Irrelevant about Ljungan. virus] · Tomas Bergström, Jan-Åke Liljeqvist Läkartidningen - 2009-01-01. Characterization of polyclonal antibodies against the capsid Parechovirus B (Ljungan virus).
Keywords: diagnosis; epidemiology; gastroenteritis; human picornavirus; parechovirus; respiratory infection. Ann Med 2001
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(Redirected from Ljungan virus) Parechovirus B, formerly called the Ljungan virus, was first discovered in the mid-1990s after being isolated from a bank vole near the Ljungan river in Medelpad county, Sweden. The first characterized non-human PeV was Ljungan virus(a member of PeV-B) found in bank voles (Clethrionomys glareolus)in Sweden near the Ljungan River. The Ljungan Virus - A Novel Pathogen The Ljungan virus was discovered in the mid-1990s. The initial findings were made among bank voles, which are the most common mammal in Scandinavia.
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Infekterade laboratoriemöss drabbas av fosterdöd och missbildningar [5]. Ljungan virus (LV), which belongs to the Parechovirus genus in the Picornaviridae family, was first isolated from bank voles (Myodes glareolus) in Sweden in 1998 and proposed as a zoonotic agent. Characterisation of the capsid proteins of cell culture-adapted Ljungan virus. lnu.se Publications.
A pathogenic virus of the viral family which includes polio and hepatitis A was isolated from a bank vole near the Ljungan river in the mid-1990s, and named Ljungan virus. Some towns near or by the river are: Matfors; Njurunda; Ånge; References
Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. It has been shown to cause type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus), and it has been suggested that it has zoonotic potential. Ljungan virus is a member of the picornavirus family, and one of the problems of this family is that we don't know how the process behind packaging the infectious RNA genome works.
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Phylogenetic analysis of Ljungan virus and A-2 plaque virus, new members of the Picornaviridae. lnu.se Publications. Simple
The virus seems to have worldwide distribution. What role the Ljungan virus is playing in cases of foetal death and various other illnesses is still, to a great extent, an unsolved puzzle.
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variation of Ljungan virus in bank voles (Myodes glareolus) in Fennoscandia. Journal of Wildlife Diseases. 53:459-471, 2017. III. Fevola C, Kuivanen S, Smura T, Vaheri A, Kallio-Kokko H, Hauffe HC, Vapalahti O, Jääskeläinen AJ. Seroprevalence of lymphocytic choriomeningitis virus and Ljungan virus
2007-04-04 Ljungan virus is a member of the picornavirus family, and one of the problems of this family is that we don't know how the process behind packaging the infectious RNA genome works. Three strains of Ljungan virus (LV) were isolated from bank voles (Clethrionomys glareolus) and A-2 plaque virus (A-2) was isolated from human sera. To study the genetic relationship between these recently discovered viruses and the members of the family Picornaviridae , an evolutionary analysis has been carried out using the amino acid sequences of the two nonstructural proteins 2C and 3D. Bank voles (Clethrionomys glareolus) kept in captivity develop diabetes mellitus to a significant extent. Also in wild bank voles, elevated blood glucose has been observed. A newly isolated picornavirus named Ljungan virus (LV) has been found in the pancreas of these bank voles.
Characterisation of the capsid proteins of cell culture-adapted Ljungan virus. lnu.se Publications. Simple search Advanced search - Research
2003; Hauffe et al. 2010; Salisbury et al.
LjV has been associated with [corrected] type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus), and it has been suggested that it has zoonotic potential. H … Ljungan virus (LV) is proposed as a potentially important rodent harbored viral human pathogen. Little is known about the biophysical nature of the virus and despite being molecularly characterized, progress in epidemiological and basic biological studies of LV has been hampered by the lack of a robust and reliable cell culture propagation system.